St. Charles County

Population: 143

Defiance is located along the Katy Trail and is known as the “Gateway to Missouri wine country,” with 4 wineries within just a couple miles.  Once home to frontiersman Daniel Boone, Defiance is rich in history and a destination area for weddings, history exploration, and recreation. Some of the most scenic parks in the St. Louis area are located in Defiance, great for hiking, biking, and canoeing.